Blar i forfatter "Suborov, Evgeny"

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    • Increased Extravascular Lung Water reduces the Efficacy of Alveolar Recruitment Maneuver in Acute Respiratory Distress Syndrome. 

      Smetkin, Alexey Anatolievich; Kuzkov, Vsevolod; Suborov, Evgeny; Bjertnæs, Lars J.; Kirov, Mikhail (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      In acute respiratory distress syndrome (ARDS) the recruitment maneuver (RM) is used to reexpand atelectatic areas of the lungs aiming to improve arterial oxygenation. The goal of our paper was to evaluate the response to RM, as assessed by measurements of extravascular lung water index (EVLWI) in ARDS patients. Materials and Methods. Seventeen adult ARDS patients were enrolled into a prospective ...

    • Inhibitor of neuronal nitric oxide synthase improves gas exchange in ventilator-induced lung injury after pneumonectomy. 

      Suborov, Evgeny; Smetkin, Alexey Anatolievich; Kondratyev, Timofey; Valkov, Andrey Yurjevich; Kuzkov, Vsevolod; Kirov, Mikhail; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Mechanical ventilation with high tidal volumes may cause ventilator-induced lung injury (VILI) and enhanced generation of nitric oxide (NO). We demonstrated in sheep that pneumonectomy followed by injurious ventilation promotes pulmonary edema. We wished both to test the hypothesis that neuronal NOS (nNOS), which is distributed in airway epithelial and neuronal tissues, could be involved in the ...

    • Physiological Changes in Subjects Exposed to Accidental Hypothermia: An Update 

      Bjertnaes, Lars J.; Næsheim, Torvind; Reierth, Eirik; Suborov, Evgeny; Kirov, Mikhail; Lebedinskii, Konstantin M.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-23)
      Background: Accidental hypothermia (AH) is an unintended decrease in body core temperature (BCT) to below 35°C. We present an update on physiological/pathophysiological changes associated with AH and rewarming from hypothermic cardiac arrest (HCA).<p> <p>Temperature Regulation and Metabolism: Triggered by falling skin temperature, Thyrotropin-Releasing Hormone (TRH) from hypothalamus induces ...

    • Postpneumonectomy pulmonary edema and the nitric oxide pathway : experimental studies in sheep 

      Suborov, Evgeny (Doctoral thesis; Doktorgradsavhandling, 2012-11-07)
      Ventilator-induced lung injury after pneumonectomy, a life-threatening complication of excessive one-lung mechanical ventilation Lung edema after lung resection is associated with a mortality of 50–100% and no cure. In sheep we found that removal of one lung followed by excessive one-lung ventilation triggered a severe lung injury with lung edema. This is a novel model of acute lung injury (ALI) ...